Parkinson’s disease is a complex movement disorder thought to affect as many as 1 million people in the United States. It is more common in older adults, affecting 10 percent of those over 80 years old. While most symptoms can be managed medically, there is currently no known cure.
It’s estimated that two-thirds of those afflicted with Parkinson’s disease struggle to get quality sleep. In fact, sleep problems are increasingly recognized as a potential early indicator of Parkinson’s disease.
Sleep disturbances in Parkinson’s patients are contributing risk factors for cognitive decline, and cognitive decline itself is known to exacerbate sleep disturbances. Additionally, sleep disturbances in those who suffer from Parkinson’s disease negatively impact daytime alertness and quality of life, not only for the patient but for the caregiver as well..
Understanding the complex interplay between Parkinson’s disease and sleep is an important step in achieving better sleep quality for Parkinson’s patients.
Despite having daytime tremors, Parkinson’s patients do not shake in their sleep. However, both Parkinson’s disease itself and the medications used to treat it can give rise to a number of sleep problems that lead to insomnia and excessive daytime sleepiness.
Patients with motor symptoms may have trouble adjusting sleeping positions to get comfortable. Others may experience distressing nocturnal hallucinations when trying to fall asleep. These may be a result of medications or cognitive impairment.
In turn, excessive daytime sleepiness (EDS) may occur as a consequence of sleeping poorly at night. It may also be triggered by medications. Parkinson’s patients who suffer from EDS may be at a higher risk of accidents and unable to safely carry out activities such as operating a motor vehicle.
Since insomnia frequently goes hand-in-hand with anxiety and depression, it may be a contributing factor to sleep problems in people with Parkinson’s disease. For that reason, doctors often look for mental health disorders in people with Parkinson’s disease who have sleep problems.
In addition to other sleep problems, people with Parkinson’s disease appear to be more susceptible to certain sleep conditions:
It’s unclear whether poor sleep causes parkinsonian symptoms to worsen or whether worsening parkinsonian symptoms cause poor sleep. In many cases it’s likely a case of bidirectionality, with each one exacerbating the other.
Fragmented sleep and sleep deprivation appear to leave the brain more vulnerable to oxidative stress, which has been tied to the development of Parkinson’s disease. Parkinson’s disease is not usually diagnosed until individuals have developed sufficient motor symptoms, by which time a significant portion of brain cells have already been damaged. If poor sleep quality or having sleep disorders foreshadows the development of parkinsonian symptoms, these could be useful in early diagnosis of the disease.
More research is needed to clarify the multifaceted relationship between Parkinson’s disease and sleep. A better understanding of this connection may offer medical experts the unique opportunity to screen at-risk individuals and perhaps delay the onset of the disease.
Parkinson’s disease is chronic and progressive, meaning it tends to get worse over time. However, there are treatment options that can help manage symptoms and allow patients to get more restful sleep.
The simplest way to start sleeping better with Parkinson’s disease is by adopting healthy sleep habits. Sleep hygiene tips for Parkinson’s disease sufferers include:
Light therapy, exercise, and deep brain stimulation have been successfully used to improve overall sleep quality and to treat specific conditions, such as REM sleep behavior disorder, in patients with Parkinson’s disease. Cognitive behavioral therapy for insomnia (CBT-I) has proven effective at reducing insomnia in healthy adults, although further research is needed on the effects of CBT in patients with Parkinson’s disease.
Patients who suspect their sleep problems may be caused by a sleep disorder should ask their doctor about appropriate testing, such a sleep study known as polysomnography. This is an overnight exam during which multiple sensors monitor sleep stages, eye movements, and other pertinent data to identify sleep disorders.
If a sleep disorder is diagnosed, treating that disorder can help address its potential consequences. For example, in patients with REM sleep behavior disorder, it is important to safety-proof the sleeping environment to avoid harm to the patient or to a sleeping partner that can happen when they act out their dreams. By contrast, a patient with obstructive sleep apnea may elect to use a CPAP machine to encourage uninterrupted breathing while sleeping.
A variety of medications and sleep aids such as melatonin are used to treat sleep-related symptoms of Parkinson’s disease. If you suffer from sleep problems, consult with your doctor before taking any over-the-counter or prescription medications. Your doctor can develop a specially adapted treatment plan to fit your situation. This may mean switching medications, managing doses, altering schedules, or cutting out medications that interfere with sleep.