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Dry Mouth At Night: What Causes It and How to Prevent It

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Jay Summer

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Dr. Abhinav Singh

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Medical Disclaimer: The content on this page should not be taken as medical advice or used as a recommendation for any specific medication. Always consult your doctor before taking any new medication or changing your current dosage.

About 22% of people experience dry mouth, also called xerostomia. Dry mouth can feel uncomfortable and negatively affect a person’s quality of life. If your mouth becomes dry at night, it might also disrupt your sleep, causing you to wake up.

We examine the symptoms, risk factors, preventative measures, and treatments for dry mouth, and discuss when it may be appropriate to talk to a doctor.

What Is Dry Mouth?

Dry mouth is the subjective sensation of having a mouth that feels dry. This condition overlaps with but differs from hyposalivation, in which a person’s glands produce too little saliva. Hyposalivation is objectively defined by measuring a person’s saliva output, while dry mouth is self-reported according to how a person’s mouth feels to them.

Symptoms

The primary symptom of xerostomia is having a dry sensation in your mouth. Doctors determine if a person has dry mouth by asking a series of questions about how their mouth feels at different times.

Many doctors and researchers use a list of symptoms called the xerostomia inventory, or a shortened version of this list. For example, medical professionals may ask questions regarding the severity of:

  • How dry your mouth feels when eating
  • How difficult it is to eat dry foods
  • How dry your lips feel
  • How dry your mouth feels at night or on awakening
  • How thirsty you feel at night

Although having a mouth that feels dry is the primary criteria, other symptoms often accompany xerostomia. The American Dental Association considers these symptoms to be complications or signs of dry mouth:

  • Bad breath
  • A burning sensation or sores in the mouth
  • Difficulty chewing, swallowing, or speaking
  • A change in taste or difficulty tolerating spicy, salty, or sour flavors
  • Dry and cracked lips
  • A rough tongue
  • Infections in the mouth
  • Trouble keeping in dentures

Chronic dry mouth can also contribute to tooth decay, plaque, eroded enamel, or tooth demineralization in the form of white spots, as well as sensitive teeth and inflamed gums.

Causes and Risk Factors

Multiple factors can cause a person to experience dry mouth, whether during the day or at night. Identifying the cause of your dry mouth may help you figure out how to treat it and prevent it from recurring.

Dehydration

If you find yourself waking up thirsty during the night or experiencing dry mouth when you wake up, you might be dehydrated. Dehydration occurs when you consume less water than your body expels, whether through urine, sweat, or other means.

Dehydration is more likely to occur when you are not drinking much water or when you are losing more fluids than usual. For example, having diarrhea or sweating due to exercise or warm weather can cause you to lose more fluids. In some cases, underlying medical issues, such as diabetes, can contribute to dehydration.

Mouth Breathing

Breathing through your mouth instead of your nose as you sleep can cause dry mouth at night. Nighttime mouth breathing can result from blocked nasal passages and is associated with sleep-disordered breathing. Working with a doctor or sleep specialist can uncover why a person breathes through their mouth at night and how to treat it.

Medications and Medical Treatments

A variety of medications can cause dry mouth as a side effect, in part because many medications interfere with saliva production. Being on more than one medication may also increase a person’s risk of dry mouth. Some medications that might lead to dry mouth include:

  • Antihistamines
  • Decongestants
  • Antidepressants
  • Antipsychotics
  • Some muscle relaxants
  • Diuretics
  • Certain stimulants used to treat attention deficit hyperactivity disorder (ADHD)
  • Bladder medications that reduce urination
  • Some sedatives
  • Some medications used to treat glaucoma
  • Some medications used to treat dementia or Parkinson’s disease
  • Certain asthma medications

Dry mouth can also result from certain medical treatments. Radiation of the head and neck as part of a cancer treatment is commonly associated with dry mouth. Continuous positive airway pressure (CPAP) machine use, a treatment for obstructive sleep apnea, has also been associated with dry mouth.

Illnesses

Sometimes dry mouth occurs as a symptom of, or along with, another physical health issue.

Dry mouth is one of the primary symptoms of Sjögren syndrome, an autoimmune disorder. Doctors often measure saliva output and check for abnormalities in saliva glands when diagnosing Sjögren syndrome. In addition to dry mouth, Sjögren syndrome often causes dry eyes. Less commonly, dryness may occur in other parts of the body.

Other illnesses and medical conditions can also cause dry mouth. Some of these illnesses include:

Aging

Dry mouth is more common in older adults. This may be due to increased use of medications that cause dry mouth.

Smoking

Toxins in cigarette smoke lead cigarette smokers to produce less saliva than non-smokers, which can result in more instances of dry mouth over time.

Biological Sex

Several studies have found that dry mouth is more prevalent in women. This prevalence is independent of medication use, meaning that it is not due to women taking more medications. More research is needed to better understand this association.

    Prevention

    There are several home remedies you can try to prevent dry mouth at night if you are at risk.

    Drink Plenty of Fluids

    If your dry mouth is mainly due to dehydration, drinking plenty of fluids might help reduce discomfort. In addition to drinking water throughout the day, consider keeping a glass of water next to your bed at night. You may also be able to stimulate saliva production before bed by chewing sugar-free gum or using a non-alcoholic mouthwash.

    Use a Humidifier

    Dry mouth may worsen when you are in a space with low humidity. Use a humidifier at night to keep your bedroom air from becoming too dry.

    Quit Smoking

    Smokers tend to produce less saliva, so quitting smoking could reduce your chances of experiencing dry mouth at night.

    Address Mouth Breathing

    If you breathe through your mouth at night due to a blocked nose or CPAP therapy, you may be able to reduce dry mouth by treating your nasal congestion or making adjustments to your CPAP setup, such as adding a humidifier to your device, in consultation with your doctor.

    Review Medications

    Check any prescription drugs, supplements, or over-the-counter medications you are taking to see if dry mouth, or xerostomia, is listed as a potential side effect. If dry mouth is a side effect of a medication you take, do not stop taking it right away. Instead, make an appointment with your doctor. They can determine if you can safely reduce your medication dosage, discontinue the medication, or change your medication schedule in order to reduce mouth dryness at night.

    Treatments

    Multiple strategies exist for treating dry mouth, depending on the root cause.

    Artificial Saliva

    Research demonstrates that saliva substitutes may relieve dry mouth in people who cannot find relief through other methods. Saliva substitutes, or artificial saliva, are lubricants that generally take the form of a gel or mouthwash. Some types of artificial saliva work better than others, so it may be helpful to consult a doctor who is familiar with the differences across types.

    Medication

    The U.S. Food and Drug Administration (FDA) has approved two salivary stimulants designed for treating dry mouth for people with certain medical conditions. Some evidence also suggests that amifostine, a medication often prescribed to reduce side effects of chemotherapy, can reduce the dry mouth associated with radiation therapy. These medications may come with their own side effects, and you should consult your doctor before starting any new medication.

    Acupuncture

    Some health professionals believe that acupuncture might be able to help treat dry mouth by stimulating saliva production, though more research is needed to confirm this theory.

    When to Talk to Your Doctor

    Not all people who experience dry mouth at night need to see a doctor. Sometimes home remedies like drinking more water, using a bedroom humidifier, or quitting smoking might solve the problem.

    Consider making an appointment with your primary care physician if:

    • Home treatments do not alleviate your symptoms
    • Dry mouth is affecting your sleep
    • Your dry mouth is accompanied by other symptoms such as dry eyes or enlarged salivary glands

    Your doctor can review the medications you take or order tests to determine if your dry mouth is due to an underlying disorder.

    People who frequently experience dry mouth may need to pay extra attention to dental care and visit their dentist more often to prevent damage to their teeth. The American Dental Association suggests using topical fluoride to reduce the risk of cavities. Your doctor can also help you treat secondary infections arising due to dry mouth.

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    About Our Editorial Team

    author
    Jay Summer

    Staff Writer

    Jay Summer is a health content writer and editor. She holds a B.S. in psychology and master's degrees in writing and public policy.

    author
    Dr. Abhinav Singh

    Sleep Physician

    MD

    Dr. Singh is the Medical Director of the Indiana Sleep Center. His research and clinical practice focuses on the entire myriad of sleep disorders.

    About Our Editorial Team

    author
    Jay Summer

    Staff Writer

    Jay Summer is a health content writer and editor. She holds a B.S. in psychology and master's degrees in writing and public policy.

    author
    Dr. Abhinav Singh

    Sleep Physician

    MD

    Dr. Singh is the Medical Director of the Indiana Sleep Center. His research and clinical practice focuses on the entire myriad of sleep disorders.

    • References

      +23 Sources
      1. 1. Agostini, B. A., Cericato, G. O., da Silveira, E. R., Nascimento, G. G., Costa, F. D., Thomson, W. M., & Demarco, F. F. (2018). How common is dry mouth? Systematic review and meta-regression analysis of prevalence estimates. Brazilian Dental Journal, 29(6), 606–618.https://pubmed.ncbi.nlm.nih.gov/30517485/
      2. 2. Plemons, J. M., Al-Hashimi, I., Marek, C. L., & American Dental Association Council on Scientific Affairs (2014). Managing xerostomia and salivary gland hypofunction: Executive summary of a report from the American Dental Association Council on Scientific Affairs. Journal of the American Dental Association (1939), 145(8), 867–873.https://pubmed.ncbi.nlm.nih.gov/25082939/
      3. 3. Nascimento, M.L., Farias, A.B., Carvalho, A.T., Albuquerque, R.F., Ribeiro, L.N., Leao, J.C., & Silva, I.-H. (2019). Impact of xerostomia on the quality of life of patients submitted to head and neck radiotherapy. Medicina Oral, Patalogia Oral, y Cirugia Bucal, 24(6), e770–e775.https://pubmed.ncbi.nlm.nih.gov/31655838/
      4. 4. Agha-Hosseini, F., & Moosavi, M.-S. (2013). An evidence-based review literature about risk indicators and management of unknown-origin xerostomia. Journal of Dentistry (Tehran, Iran), 10(3), 273–282.https://pubmed.ncbi.nlm.nih.gov/25512755/
      5. 5. Thomson, W. M., van der Putten, G.-J., de Baat, C., Ikebe, K., Matsuda, K.-I., Enoki, K., Hopcraft, M., & Ling, G. Y. (2012). Shortening the xerostomia inventory. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiation, and Endodontics, 112(3), 322–327.https://pubmed.ncbi.nlm.nih.gov/21684773/
      6. 6. Merck Manual Consumer Version. (2020, June). Quick facts: Dehydration. Retrieved August 23, 2021, fromhttps://www.merckmanuals.com/home/quick-facts-hormonal-and-metabolic-disorders/water-balance/dehydration
      7. 7. Sano, M., Sano, S., Oka, N., Yoshino, K., & Kato, T. (2013). Increased oxygen load in the prefrontal cortex from mouth breathing: A vector-based near-infrared spectroscopy study. Neuroreport, 24(17), 935–940.https://pubmed.ncbi.nlm.nih.gov/24169579/
      8. 8. Wolff, A., Joshi, R. K., Ekström, J., Aframian, D., Pedersen, A. M., Proctor, G., Narayana, N., Villa, A., Sia, Y. W., Aliko, A., McGowan, R., Kerr, A. R., Jensen, S. B., Vissink, A., & Dawes, C. (2017). A guide to medications inducing salivary gland dysfunction, xerostomia, and subjective sialorrhea: A systematic review sponsored by the World Workshop on Oral Medicine VI. Drugs in R&D, 17(1), 1–28.https://pubmed.ncbi.nlm.nih.gov/27853957/
      9. 9. Pico-Orozco, J., Carrasco-Llatas, M., Silvestre, F.-J., & Silvestre-Rangil, J. (2020). Xerostomia in patients with sleep apnea-hypopnea syndrome: A prospective case-control study. Journal of Clinical and Experimental Dentistry, 12(8), e708–e712.https://pubmed.ncbi.nlm.nih.gov/32913565/
      10. 10. Nevares, A. M. (2020, February). Sjögren syndrome. Merck Manual Professional Version. Retrieved August 24, 2021, fromhttps://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/autoimmune-rheumatic-disorders/sjögren-syndrome
      11. 11. Zhang, C., Shen, Y., Liping, F., Ma, Jing, & Wang, G.-F. (2021). The role of dry mouth in screening sleep apnea. Postgraduate Medical Journal, 97(1147), 294–298.https://pubmed.ncbi.nlm.nih.gov/32913036/
      12. 12. Mauri-Obradors, E., Estrugo-Devesa, A., Jané-Salas, E., Viñas, M., López-López, J. (2017). Oral manifestations of diabetes mellitus. A systematic review. Medicina Oral, Patologia Oral y Cirugia Bucal, 22(5), e586–e594.https://pubmed.ncbi.nlm.nih.gov/28809366/
      13. 13. Fantozzi, P. J., Pampena, E., Di Vanna, D., Pellegrino, E., Corbi, D., Mammucari, S., Alessi, F., Pampena, R., Bertazzoni, G., Minisola, S., Mastroianni, C. M., Polimeni, A., Romeo, U., & Villa, A. (2020). Xerostomia, gustatory and olfactory dysfunctions in patients with COVID-19. American Journal of Otolaryngology, 41(6), 102721.https://pubmed.ncbi.nlm.nih.gov/32977063/
      14. 14. Nizamuddin, I., Koulen, P., & McArthur, C. P. (2018). Contribution of HIV infection, AIDS, and antiretroviral therapy to exocrine pathogenesis in salivary and lacrimal glands. International Journal of Molecular Sciences, 19(9), 2747.https://pubmed.ncbi.nlm.nih.gov/30217034/
      15. 15. Mohiti, A., Eslami, F., & Dehestani, M. R. (2020). Does hypertension affect saliva properties? Journal of Dentistry (Shiraz, Iran), 21(3), 190–194.https://pubmed.ncbi.nlm.nih.gov/33062812/
      16. 16. Rad, M., Kakoie, S., Brojeni, F. N., & Pourdamghan, N. (2010). Effect of long-term smoking on whole-mouth salivary flow rate and oral health. Journal of Dental Research, Dental Clinics, Dental Prospects, 4(4), 110–114.https://pubmed.ncbi.nlm.nih.gov/23346336/
      17. 17. Niklander, S., Veas, L., Barrera, C., Fuentes, F., Chiappini, G., & Marshall, M. (2017). Risk factors, hyposalivation and impact of xerostomia on oral health-related quality of life. Brazilian Oral Research, 31, e14.https://pubmed.ncbi.nlm.nih.gov/28099580/
      18. 18. Fleming, M., Craigs, C. L., & Bennett, M. I. (2020). Palliative care assessment of dry mouth: What matters most to patients with advanced disease? Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer, 28(3), 1121–1129.https://pubmed.ncbi.nlm.nih.gov/31201546/
      19. 19. Baer, A. N., & Walitt, B. (2018). Update on Sjögren syndrome and other causes of sicca in older adults. Rheumatic Diseases Clinics of North America, 44(3), 419–436.https://pubmed.ncbi.nlm.nih.gov/30001784/
      20. 20. Łysik, D., Niemirowicz-Laskowska, K., Bucki, R., Tokajuk, G., & Mystkowska, J. (2019). Artificial saliva: Challenges and future perspectives for the treatment of xerostomia. International Journal of Molecular Sciences, 20(13), 3199.https://pubmed.ncbi.nlm.nih.gov/31261876/
      21. 21. Vinke, J., Kaper, H. J., Vissink, A., & Sharma, P. K. (2020). Dry mouth: Saliva substitutes which adsorb and modify existing salivary condition films improve oral lubrication. Clinical Oral Investigations, 24(11), 4019–4030.https://pubmed.ncbi.nlm.nih.gov/32303864/
      22. 22. Riley, P., Glenny, A.-M., Hua, F., & Worthington, H. V. (2017). Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy. The Cochrane Database of Systematic Reviews, 7(7), CD012744.https://pubmed.ncbi.nlm.nih.gov/28759701/
      23. 23. Assy, Z., & Brand, H. S. (2018). A systematic review of the effects of acupuncture on xerostomia and hyposalivation. BMC Complementary and Alternative Medicine, 18(1), 57.https://pubmed.ncbi.nlm.nih.gov/29439690/

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